Digitalis purpurea genome sequence and annotation V2doi:10.60507/FK2/4KUKXIbonndata2025-10-172Horz, Jakob; Wolff, Katharina; Friedhoff, Ronja; Pucker, Boas, 2025, "Digitalis purpurea genome sequence and annotation V2", https://doi.org/10.60507/FK2/4KUKXI, bonndata, V2Digitalis purpurea genome sequence and annotation V2doi:10.60507/FK2/4KUKXIHorz, JakobWolff, KatharinaFriedhoff, RonjaPucker, BoasbonndataPucker, BoasPucker, Boas2025-10-12Medicine, Health and Life SciencesMedicine, Health and Life SciencesHere we present a high-quality genome sequence and annotation of Digitalis purpurea (commonly known as foxglove), a plant valued both for its ornamental flowers and for producing the cardiac drug digoxin. The study aims to uncover the genetic basis of flower color variation in this species. Using ONT long-read sequencing data, we assembled the genome sequence of a magenta-flowering D. purpurea individual. We performed extensive gene prediction and functional annotation of protein-coding genes. Genes of the flavonoid biosynthesis were compared between magenta and white flowering individuals. Expression patterns were compared between different plant organs and between plants with different flower colors. Through these analyses, we identified a large insertion in the anthocyanidin synthase (ANS) that explains the differences between magenta and white flowers. This data publication contains the genome sequence with the corresponding annotation V2.<a href="http://creativecommons.org/licenses/by/4.0">CC BY 4.0</a>https://doi.org/10.24355/dbbs.084-202311130950-0Horz J. M., Wolff K., Friedhoff R., Pucker B. (2025). Genome sequence of the ornamental plant Digitalis purpurea reveals the molecular basis of flower color and morphology variation. bioRxiv. doi: 10.1101/2024.02.14.580303.10.1101/2024.02.14.580303Horz J. M., Wolff K., Friedhoff R., Pucker B. (2025). Genome sequence of the ornamental plant Digitalis purpurea reveals the molecular basis of flower color and morphology variation. bioRxiv. doi: 10.1101/2024.02.14.580303.DR1_v1.annoV2.anno.gff.gzstructural annotationapplication/gzipDR1_v1.annoV2.anno.txt.gzfunctional annotationapplication/gzipDR1_v1.annoV2.cds.fasta.gzCDSapplication/gzipDR1_v1.annoV2.genome.fasta.gzgenome sequenceapplication/gzipDR1_v1.annoV2.pep.fasta.gzapplication/gzipDR1_v1.annoV2.TEanno.gff3.gzTE annotationapplication/gzipDR1_v1.annoV2.tpms.txt.gzapplication/gzipREADME.txttext/plain