Digitalis purpurea genome sequence and annotation V2

Name: Digitalis purpurea genome sequence and annotation V2
Published: 2025-10-17
License: http://creativecommons.org/licenses/by/4.0

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Important usage condition: Use and redistribution are governed by CC BY 4.0. Review and comply with the license before using the data.

Persistent identifier: doi:10.60507/FK2/4KUKXI
Published version: 2.0
Publication date: 2025-10-17
License: CC BY 4.0

Description

Here we present a high-quality genome sequence and annotation of Digitalis purpurea (commonly known as foxglove), a plant valued both for its ornamental flowers and for producing the cardiac drug digoxin. The study aims to uncover the genetic basis of flower color variation in this species. Using ONT long-read sequencing data, we assembled the genome sequence of a magenta-flowering D. purpurea individual. We performed extensive gene prediction and functional annotation of protein-coding genes. Genes of the flavonoid biosynthesis were compared between magenta and white flowering individuals. Expression patterns were compared between different plant organs and between plants with different flower colors. Through these analyses, we identified a large insertion in the anthocyanidin synthase (ANS) that explains the differences between magenta and white flowers. This data publication contains the genome sequence with the corresponding annotation V2.

Creators

Horz, Jakob
Wolff, Katharina
Friedhoff, Ronja
Pucker, Boas

Keywords

genome sequence, flavonoids, anthocyanins, flower color, Digitalis purpurea

Files

Before downloading: Use and redistribution are governed by CC BY 4.0. Review and comply with the license before using the data.

File	Type	Bytes	Checksum
DR1_v1.annoV2.pep.fasta.gz	application/gzip	10065983	MD5 d17a91ebb87eca47913197991b4b3894
DR1_v1.annoV2.TEanno.gff3.gz	application/gzip	17873032	MD5 e74e992dfc7564b32a4b6b1ca6b641b9
DR1_v1.annoV2.anno.txt.gz	application/gzip	987469	MD5 2179d5252febbc4b188ad6f3b1742c33
DR1_v1.annoV2.cds.fasta.gz	application/gzip	15265721	MD5 9ced525920ac732079f3fb847963a2cb
DR1_v1.annoV2.anno.gff.gz	application/gzip	11509650	MD5 b4a834b262be71e66adea25643f969cd
DR1_v1.annoV2.genome.fasta.gz	application/gzip	242325975	MD5 59448232c618051c46b7cab5b883414c
DR1_v1.annoV2.tpms.txt.gz	application/gzip	3492734	MD5 8ebad11ddabd3089c7412637feed3753
README.txt	text/plain	5477	MD5 c6c59131bf68c23eb13db4d44a9c5dd5

Citation

Horz, Jakob; Wolff, Katharina; Friedhoff, Ronja; Pucker, Boas, 2025-10-17, Digitalis purpurea genome sequence and annotation V2, doi:10.60507/FK2/4KUKXI, V2.0

Additional Dataverse fields

Id	581
Dataset Type	dataset
Internal Version Number	11
Latest Version Publishing State	RELEASED
Release Time	2026-02-15T16:57:58Z
Create Time	2026-02-15T16:32:16Z
Citation Date	2025-10-17
File Access Request	True

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Citation Metadata

Title title

Digitalis purpurea genome sequence and annotation V2

Author author

Author Name
Horz, Jakob
Author Affiliation
University of Bonn
Author Identifier Scheme
ORCID
Author Identifier
Type Name
authorIdentifier
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https://orcid.org/0009-0007-7367-9439
Expandedvalue
Person Name
Horz, Jakob
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Scheme
ORCID
@type
https://schema.org/Person
Author Name
Wolff, Katharina
Author Affiliation
University of Bonn
Author Identifier Scheme
ORCID
Author Identifier
0000-0002-3616-0482
Author Name
Friedhoff, Ronja
Author Affiliation
TU Braunschweig
Author Identifier Scheme
ORCID
Author Identifier
Type Name
authorIdentifier
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False
Type Class
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Value
https://orcid.org/0009-0002-0270-4661
Expandedvalue
Person Name
Friedhoff, Ronja
@id
https://orcid.org/0009-0002-0270-4661
Scheme
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@type
https://schema.org/Person
Author Name
Pucker, Boas
Author Affiliation
University of Bonn
Author Identifier Scheme
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Type Name
authorIdentifier
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Value
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Expandedvalue
Person Name
Pucker, Boas
@id
https://orcid.org/0000-0002-3321-7471
Scheme
ORCID
@type
https://schema.org/Person

Dataset Contact datasetContact

Dataset Contact Name
Pucker, Boas
Dataset Contact Affiliation
University of Bonn
Dataset Contact Email
pucker@uni-bonn.de

Ds Description dsDescription

Ds Description Value
Here we present a high-quality genome sequence and annotation of Digitalis purpurea (commonly known as foxglove), a plant valued both for its ornamental flowers and for producing the cardiac drug digoxin. The study aims to uncover the genetic basis of flower color variation in this species. Using ONT long-read sequencing data, we assembled the genome sequence of a magenta-flowering D. purpurea individual. We performed extensive gene prediction and functional annotation of protein-coding genes. Genes of the flavonoid biosynthesis were compared between magenta and white flowering individuals. Expression patterns were compared between different plant organs and between plants with different flower colors. Through these analyses, we identified a large insertion in the anthocyanidin synthase (ANS) that explains the differences between magenta and white flowers. This data publication contains the genome sequence with the corresponding annotation V2.
Ds Description Date
2025-10-16

Subject subject

Medicine, Health and Life Sciences

Subject Refinement subjectRefinement

Subject Refinement Value
Plant Biology

Free Keyword freeKeyword

Free Keyword Value
genome sequence
Free Keyword Value
flavonoids
Free Keyword Value
anthocyanins
Free Keyword Value
flower color
Free Keyword Value
Digitalis purpurea

Publication publication

Publication Relation Type
Cites
Publication Citation
Horz J. M., Wolff K., Friedhoff R., Pucker B. (2025). Genome sequence of the ornamental plant Digitalis purpurea reveals the molecular basis of flower color and morphology variation. bioRxiv. doi: 10.1101/2024.02.14.580303.
Publication IDType
doi
Publication IDNumber
10.1101/2024.02.14.580303
Publication URL
https://doi.org/10.1101/2024.02.14.580303

Language language

English

Depositor depositor

Pucker, Boas

Date Of Deposit dateOfDeposit

2025-10-12

Related Datasets relatedDatasets

https://doi.org/10.24355/dbbs.084-202311130950-0

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